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NFL Week 4 Betting: Best early bets before lines move

2Y5P43M Philadelphia Eagles players celebrate after Reed Blankenship, third from left, intercepted a pass that ended the New Orleans Saints' final drive in the fourth quarter of an NFL football game in New Orleans, Sunday, Sept. 22, 2024. (AP Photo/Gerald Herbert)

• Bet the Eagles (-2.5) to take care of the Buccaneers: These teams are in completely different tiers right now, and a matchup between them should see the Eagles favored by a field goal or more, which is where this line should close come Sunday.

• Tampa Bay is coming off a rough loss: The Buccaneers' secondary was carved up by rookie Bo Nix, who had struggled immensely before the impressive performance. The Buccaneers' run defense has also been a real issue, grading out third worst in the NFL.

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NFL Week 3 is nearly a wrap, and betting lines are now available for Week 4. Here are our favorite early spread picks for the slate.

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